First, use the Spicify effect to boost the color, contrast and detail in an image. Then, use the Noise tab (click the Use Topaz DeNoise™ box) and reduce the noise to the point where your picture becomes very blurry - as illustrated in the top image, which I created from a similar image to the bottom image.
I found that working on a low resolution image, and then up-sizing it, works better than working on a full resolution image.
If you are new to Topaz products, you can save a bundle by choosing a bundle.
By they way, when using this technique, you remove some of the reality in a scene. When you remove some of the reality, your picture can become more artistic and creative.
Explore the Light,
Rick